The reconstruction
When a major bile duct injury cannot be managed endoscopically — generally the case for Strasberg E-class injuries and higher — surgical reconstruction is required. The standard operation is a Roux-en-Y hepaticojejunostomy, first popularized by Hepp and Couinaud and refined over decades of hepatobiliary practice. The surgeon mobilizes a segment of jejunum, divides it to create a long Roux limb, brings that limb up through the mesocolon to the porta hepatis, and anastomoses it directly to the healthy hepatic ducts above the zone of injury. The distal jejunum is then reconnected lower down (the jejunojejunostomy) to restore enteric continuity.
The operation is most successful when performed by a high-volume hepatobiliary surgeon at a specialized center, roughly 4–8 weeks after the original injury — enough time for acute inflammation to subside and for the proximal biliary anatomy to declare itself clearly. Large retrospective series from major hepatobiliary centers report long-term anastomotic patency rates of roughly 70%–90% at ten years, with the range driven largely by the level of the original injury (higher injuries are technically harder) and the experience of the reconstructive team.
In a minority of cases — particularly injuries caught in the first 72 hours — a simpler repair (duct-to-duct anastomosis) may be feasible. Later repairs, injuries involving the biliary confluence (Strasberg E3–E5), and repairs in patients with hepatic-lobe atrophy almost always require the Roux-en-Y approach. What's more, the technical variant matters: bilateral ductoplasty, wide mucosa-to-mucosa anastomosis, and absorbable suture technique each have documented effects on stricture rates.


